Abstract: Through the analysis of residual coal spontaneous combustion case in a gob of Renlou mine Ⅱ₁ mining area,the influence of cross uphill mining on gob spontaneous combustion is elaborated.The results show that coal pillar should not be left at cross uphill mining working face.If must put coal pillars,the coal pillar should be special treated to prevent spontaneous combustion.After working face stopping work,building intake air side closed wall firstly,building return air side closed wall secondly,wind trend in gob can be prevent to change.