Abstract: Aiming at a series of mining problems in No.12 mine of Pingdingshan Tian’an Coal Mining Company, such as coal seam gas control, gangue emission pollution, high gas and low permeability without conventional protective layer, the integrated circulation mining mode of “mining, selection, drainage, filling and mining” was comprehensively applied. The traditional backward mining concept was abandoned. It fundamentally solves the problem of gas prevention of high gas and outburst coal seam in No.12 mine, alleviates the environmental pressure caused by gangue stacking in a kilometer deep well, realizes the cooperative mining of coal and gas in the coal seam with high gas and low permeability without conventional protection layer, and greatly improves the coal output in No.12 mine. The successful application of “mining, selection, drainage, filling, mining” circulation mining mode in No.12 coal mine provides an integrated technical way for safe and efficient mining of high gas and low permeability coal seam.