Abstract: In order to reduce the pipeline network resistance of gas drainage system, improve the efficiency of it, by calculating the network resistance of mine pipeline and branch of gas drainage system, the gas drainage network chart has been drawn. The pipeline network resistance distribution is got. The pipe diameter of gas drainage is adjusted for local high resistance. The results show that through the optimization of gas drainage pipe network system, the gas drainage pipeline resistance is reduced, the gas drainage concentration and quantity of drainage are significantly improved. The influence of gas on mining space is reduced. The comprehensive gas control is realized.