Abstract: The properties, advantages and disadvantages about nature ventilation volume distribution algorithm of complex mine ventilation networks are sumed up. In order to improve the performance of nature ventilation volume distribution algorithms of complex mine ventilation networks, the nature ventilation volume distribution algorithms of complex mine ventilation networks based on genetic algorithm are put forward, which combines genetic algorithm and the basic theory of nature ventilation volume distribution of mine ventilation networks with traditional no-linear equations algorithms. The nature ventilation volume distribution algorithms of complex mine ventilation networks based on genetic algorithm is divided into direct algorithm and indirect algorithm, the two algorithms are implemented and the traits of the two algorithms are compared.