Abstract: This paper introduces difficulties of fire prevention and extinguishing in high gas and easy spontaneous combustion seam, and pointed out the effect of rockburst on spontaneous combustion of coal. The experiment tested the change law of spontaneous combustion index gas in Hujiahe Coal Mine 401101 working face, which provided a scientific basis for coal spontaneous combustion forecast of working face. The paper elaborated implementation programs and parameters of comprehensive fire prevention technology including upper and lower corner sealing, gel wall isolation, covering a wide range float coal with three-phase bubble during mining period.