Abstract: To improve the level of mine gas control technology and corresponding equipment of Shuikuang Group and actively respond to the call of science and technology development in 13th five-year plan period of China coal industry, a demonstrative experimental research of hydraulic fracturing by crossing borehole in Dawan Mine west well is carried out, and the application of this technology under special geological conditions in Guizhou soft and low permeability coal seam is investigated. The results show that the technology can effectively improve the permeability of coal and rock mass and the effect of drilling gas drainage, gas permeability coefficient of fracturing zone in coal seam was increased 18.37 times. The radius influenced by hydraulic fracturing was 40 m. The single-hole gas drainage concentration and pure gas drainage capacity were increased over 2 times than original coal seam.