Abstract: Taking main fan as the monitoring object, the communication module based on CP340/341 organically links the various parts involved in the monitoring system, which successfully achieves the communication of the devices such as control unit, temperature inspection instrument and high-voltage cabinet system. The achievement of communication provides the convenience for the writing of monitoring function programs, the optimization and upgrade of system function, and it can reduce the cost of hardware. Put into operation in one of the mines of the Shandong Energy successfully, the system has the functions of operating parameters real-time supervision, one-button operation, automatic air return, early warming and data reporting of fault. It provides a significant guarantee and technical support for the safe operation of the main fan.