Abstract: According to the present situation of occupational hazards of coal mine in China and relevant occupational health technical standard, in order to make a comprehensive evaluation of the current situation of mine occupational hazards in China, taking coal dust, ash, nitrogen oxides, sulfur dioxide, carbon monoxide, high temperature, noise as evaluation factors, we establish damage weighting function by AHP (analytic hierarchy process) and fuzzy evaluation, and obtain main harmful factors for coal dust and ash. The comprehensive damage degree of each evaluation site from heavy to light is anchor and shotcrete support point, rock tunnel heading face, fully-mechanized working face, coal roadway heading face, machine repair shop and electromechanical chamber. The comprehensive hazard of occupational diseases in different locations in the mine is judged.