Abstract: In order to solve the problem of stress concentration and rock burst hazards resulted from work face mining in a thousand meters deep coal mine, this paper proposes a comprehensive monitoring and prevention technology system of “dividing risk areas before mining+pressure relief in advance+comprehensive monitoring+strengthening support+releasing stress to eliminate risk+testing the effect”; the multi-factor coupling method was used to analyze the pre-mining risk in the working face area and carry out the pre-unloading treatment; with the mining of work face, using the dynamic multi-scale monitoring method of “real-time monitoring+medium-term monitoring+long-term monitoring” and “regional monitoring+ local monitoring + point monitoring” to monitor and test the danger in the impact danger area; after determining the rock burst risk, measures of strengthening the support, releasing stress and testing effect are taken and the impact risk is relieved. This system is used in identifying stress concentration area of E3207 face track lane 32° corner point area before and during the mining in Xingcun Coal Mine and immediate pressure relief has taken.