Abstract: Based on the analysis of the characteristics of water inrush from the anchor hole in a coal mine in Ordos Basin, the water chemistry analysis method was used to determine the sandstone water of Zhiluo Formation in which the water source of the anchor cable hole was communicated with the water channel of the roof. The outlet channel is a through-hole fracture between the borehole and the surrounding rock of the roof. Aiming at the characteristics of weak roof rock layer and high water pressure, the treatment plan of “water drainage and pressure relief +bottom low pressure reinforcement grouting+top high pressure sealing grouting” was proposed and implemented. After the implementation of the site, the high-pressure water inrush from the borehole was effectively blocked, the water reduction rate was up to 100%, and the surrounding rock of the roadway was stable.