Abstract: Based on the typical layered heterogeneous structure model of the borehole seal segment, this paper studies the uncoordinated deformation characteristics of the layered heterogeneous structure of the borehole seal segment by using elastic mechanics and thick-wall cylinder theory, and the influential factors and the influential scale are numerically analyzed. The analysis results show that the air leakage crack between the heterogeneous structures in the borehole sealing section is mainly caused by the radial and tangential uncoordinated deformation damage at the interface, and the physical and mechanical properties of the coal and rock are E, v, the surrounding rock stress p, and the stress transfer coefficient k, the frictional resistance coefficient f of the contact surface and the material thickness (the inner and outer diameter ratio τ) are the main factors causing the uncoordinated deformation between the heterogeneous structures of the drilled sealing section.