Abstract: Water inrush accident occurred at 1309 working face of a coal mine in Hebi city, with the sudden water amount between 1 700 m³/h and 1 950 m³/h, and the water inrush peak value of 4 291 m³/h, resulting in flooding well. According to the uncertain location of water inrush point and water inrush channel, large amount of water inrush, high water pressure, complicated geological structure (concealed structure water inrush) and so on, the vertical borehole and stereoscopic branch of horizontal directional drilling with the combination of rapid plugging water bursting point technology is used. Based on the source plugging and combined with plugging, three-dimensional grouting sealing and reinforcement is carried out for the Ordovician limestone, L₂ limestone aquifer and main water channel of F₁₀₆₁ fault zone where the water inrush point is located, and the curtain is formed to cut off the deep water inrush channel, and the water blocking effect is remarkable, which achieves the purpose of quick grouting water blocking and drainage and mine discharge reduction.