Abstract: The Morgan Stanley-Pryss method and the finite difference method are used to analyze and evaluate the stability of the layered soft rock slope under the two conditions of water-free and rainy season water level, and the slope of the stope and dump in Shunxing Open-pit Coal Mine. As an example, the results show that the stability of the D2 stability of the slope of the southern slope of the stope is the largest, reaching 29.63%; the weakening of the D3 section of the western slope is the smallest, only 0.14%. The main reason is that the exposed area of the southern slope is larger than other slopes. Under the influence of rainfall, the water level line inside the southern slope is immersed in the potential slip surface, which increases the bulk density and water pressure of the sliding surface of the potential slip surface. The slope safety factor has dropped dramatically. The landslide prevention engineering measures combined with slope reduction, internal pressure relief and drainage and drainage can effectively improve the slope stability and prevent the formation of landslides.