Abstract: A roadway support optimization method based on parametric numerical calculation inversion analysis is proposed. Based on the measured values, the geomechanical parameters with less error between the calculated results and the actual mineralization are obtained through the inversion analysis of parameterized numerical calculation, so as to evaluate the support effect of different support schemes. On the basis of the establishment of optimization process of support scheme, taking 3210 isolated island working face of Wangpo Mine as an example, the optimization comparison and selection of different support schemes are carried out. The results show that the accuracy of the numerical calculation method is improved by introducing the measured data of ground pressure as the accuracy evaluation condition of the numerical model. In order to improve the calculation efficiency, the easily observed ground pressure behavior parameters should be selected as the dependent variables of parametric inversion analysis.