Abstract: In order to avoid the blindness of the hydraulic fracturing of the directional long borehole in coal mine 2130 of Xinjiang Coking Coal Group, and to accurately grasp the extension and expansion of hydraulic fracturing under different hole layout methods, this paper uses the numerical simulation method to carry out hydraulic fracturing numerical simulation for comb directional long borehole in 4# coal seam of coal mine 2130 with a buried depth of 500 m. The simulation results show that the different hole layout methods have obvious effects on hydraulic fracturing initiation pressure, crack initiation position, fracture mode and crack extension and expansion law, combined with the actual situation of 4# coal seam in coal mine 2130, the optimal drilling hole layout method and fracturing parameters are optimized for engineering practice, and good fracturing results have been achieved. Compared with the previous hydraulic fracturing measures at this level, the drainage concentration is increased by 2.7 times, and the scalar amount of drainage increased by 11.8 times.