Abstract: Based on the detailed investigation on the coal fire area of Rujigou Coal Mine, through deeply understanding production and technical conditions of NO.335 fully mechanized face, the paper conducted analysis and investigation to fire risks that may affect safe mining, on this basis the paper proposed fire prevention and extinguishing technology program for safe mining in fully mechanized face fire. Practice shows that injecting liquid nitrogen, grouting and Rockshow material handling, blocking shady fire district in shady slope fire zone around 335 mechanized mining face and 335 working face overlying No.2₁ seam goaf and inerting No.2₂ seam goaf, can effectively curb the continuing influence of the shady slope of the fire zone and the overlying No.2₁ and No.2₂ seam goaf on safety mining of 335 working face in Rujigou mine, which ensures the safe mining of the face.