Abstract: In order to solve the problem of instability and failure of deep antegrade slope, taking Fushun West Open-pit Mine as an example, the occurrence law of weak layer and the delimitation of deformation boundary are determined by engineering drilling and monitoring data tracking analysis method; based on the strength reduction and back analysis method, the mechanical indexes of rock and soil mass are obtained; using limit equilibrium and three-dimensional finite difference method, the variation laws of different internal drainage height and slope stability are analyzed; the monitoring data tracking analysis is used to evaluate the control effect. The results show that the results of two-dimensional limit equilibrium and three-dimensional finite element analysis are highly consistent. When the inner row height is 80 m, the stability meets the safety requirements. The monitoring data are tracked and analyzed, and the inner row scheme can realize the control of slope stability.